In northern Australia at the beginning of World War II, an English aristocrat inherits a cattle station the size of Maryland. When English cattle barons plot to take her land, she reluctantly joins forces with a rough-hewn stock-man to drive 2,000 head of cattle across hundreds of miles of the country's most unforgiving land, only to still face the bombing of Darwin, Australia, by the Japanese forces that had attacked Pearl Harbor only months earlier.

In 1986, Saroo was a five-year-old child in India of a poor but happy rural family. On a trip with his brother, Saroo soon finds himself alone and trapped in a moving decommissioned passenger train that takes him to Calcutta, 1500 miles away from home. Now totally lost in an alien urban environment and too young to identify either himself or his home to the authorities, Saroo struggles to survive as a street child until he is sent to an orphanage. Soon, Saroo is selected to be adopted by the Brierley family in Tasmania, where he grows up in a loving, prosperous home. However, for all his material good fortune, Saroo finds himself plagued by his memories of his lost family in his adulthood and tries to search for them even as his guilt drives him to hide this quest from his adoptive parents and his girlfriend. Only when he has an epiphany does he realize not only the answers he needs, but also the steadfast love that he has always had with all his loved ones in both worlds.